東京大学 大学院薬学系研究科 薬品作用学教室

学会発表はこちら

2019

• Kono, R., Kim, G., Nagata, H., Ikegaya, Y., Koyama, R. Induced neuronal activity does not attenuate amyloid beta-induced synapticloss in vitro. Neuropsychopharmacol. Rep., in press.
• Orita, K., Sawada, K., Koyama, R., Ikegaya, Y. Deep learning-based quality control of cultured human-induced pluripotent stem cell-derived cardiomyocytes. J. Pharmacol. Sci., in press.
• Konno, D., Nakayama, R., Tsunoda, M., Funatsu, T., Ikegaya, Y., Sasaki, T. Collection of biochemical samples with brain-wide electrophysiological recordings from a freely moving rodent. J. Pharmacol. Sci., in press.
• Noguchi, A., Sakaguchi, T., Sato, M., Aikawa, H., Matsumoto, N., Ikegaya, Y. Whisker electromyograms signify awake and anesthetized states in mice. Neurosci. Res., in press.
• Motegi, Y., Sato, M., Horiguchi, K., Ohkura, M., Gengyo-Ando, K., Ikegaya, Y., Fusamae, Y., Hongo, Y., Suzuki, M., Ogawa, K., Takaki, M., Nakai, J. Confocal and multiphoton calcium imaging of the enteric nervous system in anesthetized mice. Neurosci. Res., in press.
• Nakashima, A., Ihara, N., Shigeta, M., Kiyonari, H., Ikegaya, Y., Takeuchi, H. Structured spike series specify gene expression patterns for olfactory circuit formation. Science, 365:eaaw5030, 2019. recommended in F1000 prime.
• Nakano, R., Ihara, N., Morikawa S., Kanemaki, M., Ikegaya, Y., Takeuchi, H. Auxin-mediated rapid degradation of target proteins in hippocampal neurons. Neuroreport, 30:908-913, 2019.
• Nakayama, R., Ikegaya, Y., Sasaki, T. Cortical-wide functional correlations are associated with stress-induced cardiac dysfunctions in individual rats. Sci. Rep., 9:10581, 2019.
• Nomura, H., Mizuta, H., Norimoto, H., Masuda, F., Miura, Y., Kubo, A., Kojima, H., Ashizuka, A., Matsukawa, N., Baraki, Z., Hitora-Imamura, N., Nakayama, D., Ishikawa, T., Okada, M., Orita, K., Saito, R., Yamauchi, N., Sano, Y., Kusuhara, H., Minami, M., Takahashi, H., Ikegaya, Y. Central histamine boosts perirhinal cortex activity and restores forgotten object memories. Biol. Psychiat., 86: 230-239, 2019.
• Sasaki, T. A physiolomics approach to reveal systemic organ dynamics in a rodent. Biol. Pharm. Bull., 42:1059-1063, 2019.
• Andoh, M., Shibata, K., Okamoto, K., Onodera, J., Morishita, K., Miura, Y., Ikegaya, Y., Koyama, R. Exercise reverses behavioral and synaptic abnormalities after maternal inflammation. Cell Rep., 27:2817-2825, 2019.
• Abe, R., Okada, S., Nakayama, R., Ikegaya, Y, Sasaki, T. Social defeat stress causes selective attenuation of neuronal activity in the ventromedial prefrontal cortex. Sci. Rep., 9:9447, 2019. recommended in F1000 prime.
• Kashima, T., Noguchi, A., Ikegaya, Y., Matsumoto, N. Heterogeneous expression patterns of fibronectin in the mouse subiculum. J. Chem. Neuroanat., 98:131-138, 2019.
• Sasaki, T., Suzuki, I., Yokoi, R., Sato, K., Ikegaya, Y. Synchronous spike patterns in differently mixed cultures of human iPSC-derived glutamatergic and GABAergic neurons. Biochem. Biophy. Res. Commun., 513:300-305, 2019.
• Aoki, Y., Igata, H., Ikegaya, Y., Sasaki, T. Integration of goal-directed signals onto spatial maps of hippocampal place cells. Cell Rep., 27:1516-1527, 2019.
• Nomura, H., Teshirogi, C., Nakayama, D., Minami, M., Ikegaya, Y. Prior observation of fear learning enhances subsequent self-experienced fear learning with an overlapping neuronal ensemble in the dorsal hippocampus. Mol. Brain, 12:21, 2019.
• Gao, M., Orita, K., Ikegaya, Y. Maternal immune activation in pregnant mice produces offspring with altered hippocampal ripples. Biol. Pharmaceut. Bull., 42:666-670, 2019.
• Kasahara, Y., Igata, H., Sasaki, T., Ikegaya, Y., Koyama, R. The pharmacological assessment of GABAA receptor activation in experimental febrile seizures in mice. eNeuro, e0429-18, 2019.
• Shikano, Y., Nishimura, Y., Okonogi, T., Ikegaya, Y., Sasaki, T. Vagus nerve spiking activity associated with locomotion and cortical arousal states in a freely moving rat. Eur. J. Neurosci., 49:1298-1312, 2019.
• Kobayashi, C., Okamoto, K., Mochizuki, Y., Urakubo, H., Funayama, F., Ishikawa, T., Kashima, T., Szymanska, A. F., Ouchi, A., Ishii, S., Ikegaya, Y. GABAergic inhibition reduces the impact of synaptic excitation on somatic excitation. Neurosci. Res., 146:22-35, 2019.
• Sasaki, T., Non-structured spike sequences of hippocampal neuronal ensembles in awake animals. Neurosci. Res., 142:1-6, 2019.
• Okamoto, K., Ikegaya, Y. Recurrent connections between CA2 pyramidal cells. Hippocampus, 29:305-312, 2019.
• Zhou, Z., Ikegaya, Y., Koyama, R., The astrocytic cAMP pathway in health and disease. Int. J. Mol., 20:779, 2019.
• Sato, Y., Miyawaki, T., Ouchi, A., Noguchi, A., Yamaguchi, S., Ikegaya, Y. Quick visualization of neurons in brain tissues using an optical clearing technique. Anat. Sci. Int., 94:199-208, 2019.
• Kayama, T., Okamoto, K., Gao, M., Ikegaya, Y., Sasaki, T. Immature electrophysiological properties of human-induced pluripotent stem cell-derived neurons transplanted into the mouse cortex for seven weeks. Neuroreport, 30:169-173, 2019.
• Sanders, H., Ji, D., Sasaki, T., Leutgeb, J. K., Wilson, M. A., Lisman, J. E. Temporal coding and rate remapping: Representation of non-spatial information in the hippocampus. Hippocampus, 29:111-127, 2019.
• 小林千晃、抑制性シナプス入力による興奮性シナプス入力の無効化、神経科学ニュース、219:25-28, 2019.
• 大内彩子、佐々木拓哉、池谷裕二、海馬神経同期発火の生理的意義に関する最近の知見、月刊「細胞」、51:266-269, 2019.
• 中山亮太、池谷裕二、佐々木拓哉、末梢臓器動態に基づく動物の精神状態の評価、日本薬理学雑誌、153: 161-164, 2019.
• 池谷裕二、奨励賞受賞佐々木拓哉氏の業績、ファルマシア、55:579, 2019

2018

• Iwasaki, S., Ikegaya, Y. In vivo one-photon confocal calcium imaging of neuronal activity from the mouse neocortex. J. Integr. Neurosci., 17:671-678, 2018.
• Katori, K., Manabe, H., Nakashima, A., Eerdunfu, Sasaki, T., Ikegaya, Y., Takeuchi H. Sharp wave-associated activity patterns of cortical neurons in the mouse piriform cortex. Eur. J. Neurosci., 48:3246-3254, 2018.
• Shikano, Y., Sasaki, T., Ikegaya, Y., Monitoring brain neuronal activity with manipulation of cardiac events in a freely moving rat. Neurosci. Res., 136:56-62, 2018.
• Sakamoto, S., Takeuchi, H., Ihara, N., Bao Ligao, B., Suzukawa, K. Possible requirement of executive functions for high performance in soccer. PLOS ONE, 13:e0201871, 2018.
• Sakaguchi, T., Iwasaki, S., Okada, M., Okamoto, K., Ikegaya, Y. Ethanol facilitates socially-evoked memory recall in mice by recruiting pain-sensitive anterior cingulate cortical neurons. Nat. Commun., 9:3526, 2018.
• Sato, M., Matsumoto, N., Noguchi, A., Okonogi, T., Sasaki, T., Ikegaya, Y. Simultaneous monitoring of mouse respiratory and cardiac rates through a single precordial electrode. J. Pharmacol. Sci., 137:177-186, 2018.
• Desantis, A., Haggard, P., Ikegaya, Y., Hagura, N. Specificity of action selection modulates the perceived temporal order of action and sensory events. Exp. Brain Res., 236:2157-2164, 2018.
• Hoshi, Y., Okabe, K., Shibasaki, K., Funatsu, T., Matsuki, N., Ikegaya, Y., Koyama, R. Ischemic brain injury leads to brain edema via hyperthermia-induced TRPV4 activation. J. Neurosci., 38:5700-5709, 2018.
• Yagi, S., Igata, H., Shikano, Y., Aoki, Y., Sasaki, T., Ikegaya, Y. Time-varying synchronous cell ensembles during consummatory periods correlate with variable numbers of place cell spikes. Hippocampus, 28:471-483, 2018.
• Okamoto, K., Hitora-Imamura, N., Hioki, H., Ikegaya, Y. GABAergic malfunction in the anterior cingulate cortex underlying maternal immune activation-induced social deficits. J. Neuroimmunol., 321:92-96, 2018.
• Koyama, R., Ikegaya, Y. The molecular and cellular mechanisms of axon guidance in mossy fiber sprouting. Front. Neurol., 9:382, 2018.
• Kasahara Y., Ikegaya, Y., Koyama, R. Neonatal seizure models to study epileptogenesis. Front. Pharmacol., 9:385, 2018.
• Yawata, Y., Makino, K., Ikegaya, Y. Answering hastily retards learning. PLOS ONE, 13:e0195404, 2018.
• Chang, D.H.F., Ban, H., Ikegaya, Y., Fujita, I., Troje, N.F. Cortical and subcortical responses to biological motion. Neuroimage, 174:87-96, 2018.
• Okonogi, T., Nakayama, R., Sasaki, T., Ikegaya, Y. Characterization of peripheral activity states and cortical local field potentials of mice in an elevated plus maze test. Front. Behav. Neurosci., 12:62, 2018.
• Shikano, Y., Sasaki, T., Ikegaya, Y., Simultaneous recordings of cortical local field potentials, electrocardiogram, electromyogram, and breathing rhythm from a freely moving rat. J. Vis. Exp., 134:e56980, 2018.
• Norimoto, H., Makino, K., Gao, M., Shikano, Y., Okamoto, K., Ishikawa, T., Sasaki, T., Hioki, H., Fujisawa, S., Ikegaya, Y. Hippocampal ripples down-regulate synapses. Science, 359:1524-1527, 2018.
• Hiragi, T., Ikegaya, Y., Koyama, R. Microglia in Epilepsy. Cells, 7:26, 2018.
• Sasaki, T., Piatti, V. C., Hwaun, E., Ahmadi. S., Lisman, J. E., Leutgeb, S., Leutgeb, J. Dentate network activity is necessary for spatial working memory by supporting CA3 sharp-wave ripple generation and prospective firing of CA3 neurons. Nat. Neurosci., 21:258-269, 2018.
• Kayama, T., Suzuki, I., Odawara, A., Sasaki, T., Ikegaya, Y. Temporally coordinated spiking activity of human induced pluripotent stem cell-derived neurons co-cultured with astrocytes. Biochem. Biophys. Res. Commun., 495:1028-1033, 2018.
• 佐々木拓哉、神経回路とシナプス動態を繋ぐ研究の一例、細胞、50:151, 2018.
• 牧野健一、ひらめきに付随する「アハ体験」とドパミンの神経相関、ファルマシア、54:1166, 2018.
• 大柿安里、池谷裕二、小山隆太、ミクログリアは免疫記憶するか？、実験医学、36:2222-2223, 2018.
• 牧野健一、池谷裕二、記憶を促通する学習パラダイムとその原理、Brain and Nerve、70:821-828, 2018.
• 鹿野悠、佐々木拓哉、池谷裕二、海馬神経細胞の時間表象、Brain and Nerve, 69:1233-1239, 2018.
• 高夢璇、佐藤元重、池谷裕二、人工知能を用いた薬物副作用の予測、薬学雑誌、138:809-813, 2018.
• 佐藤薫、池谷裕二、神経系非臨床試験のヒト予測性向上への挑戦 ―― 人工知能（AI）及びヒト神経細胞マテリアルの可能性、薬学雑誌、138:807, 2018.
• 折田健、渡邉裕亮、池谷裕二、AIを用いた治療薬の有効性、副反応、薬物相互作用の評価、腎臓、40:19-22, 2018.

2017

• Okada, S., Igata, H., Sasaki, T., Ikegaya, Y. Spatial representation of hippocampal place cells in a T-maze with an aversive stimulation. Front. Neural Circuits, 11:101, 2017.
• Hiragi, T., Andoh, M., Araki, T., Shirakawa, T., Ono, T., Koyama, R., Ikegaya, Y. Differentiation of human induced pluripotent stem cell (hiPSC)-derived neurons in mouse hippocampal slice cultures. Front. Cell. Neurosci., 11:143, 2017.
• Minamisawa, G., Funayama, K., Matsumoto, N., Matsuki, N., Ikegaya, Y. Flashing lights induce prolonged distortions in visual cortical responses and visual perception. eNeuro, 4, 2017.
• Noguchi, A., Matsumoto, N., Morikawa, S. Tamura, H., Ikegaya, Y. Juvenile hippocampal CA2 region expresses aggrecan. Front. Neuroanat., 11:41, 2017.
• Watanabe, Y., Ikegaya, Y. Caffeine increases hippocampal sharp waves in vitro. Biol. Pharm. Bull., 40:1111-1115, 2017.
• Ouchi, A., Matsumoto, N., Ikegaya, Y. Activation of hilar mossy cells and dentate granule cells during sharp wave/ripples. Curr. Res. Neurosci., 7:1-8, 2017.
• Sasaki, T., Nishimura, Y., Ikegaya, Y. Simultaneous recordings of central and peripheral bioelectrical signals in a freely moving rodent. Biol. Pharm. Bull., 40:711-715, 2017.
• Ihara, N., Ikegaya, Y., Takeuchi, H. Quadruple immunostaining of the olfactory bulb for visualizing the molecular identity codes of olfactory sensory axons. J. Vis. Exp., 124, 2017.
• Aoki, Y., Nishimura, Y., Hondrich, T., Nakayama, R., Igata, H., Sasaki, T., Ikegaya, Y. Selective attenuation of electrophysiological activity of the dentate gyrus in a social defeat mouse model. J. Physiol. Sci., 67:507-513, 2017.
• Ujita, S., Sasaki, T., Asada, A., Funayama, K., Gao, M., Mikoshiba, K., Matsuki, N., Ikegaya, Y. cAMP-dependent calcium oscillations of astrocytes: an implication for pathology. Cereb. Cortex, 27:1602-1614, 2017.
• Hirabayashi, K., Hanaoka, K., Egawa, T., Kobayashi, C., Takahashi, S., Komatsu, T., Ueno, T., Terai, T., Ikegaya, Y., Nagano, T., Urano, Y. Synthesis of practical red fluorescent probe for cytoplasmic calcium ions with greatly improved cell-membrane permeability. Data Brief, 12:351-357, 2017.
• Dunfu, E., Ihara, N., Ligao, B., Ikegaya, Y., Takeuchi, H. Differential timing of neurogenesis underlies dorsal-ventral topographic projection of olfactory sensory neurons. Neural Dev., 12:2, 2017.
• Morikawa, S., Ikegaya, Y., Narita, M., Tamura, H. Activation of perineuronal net-expressing excitatory neurons during associative memory encoding and retrieval. Sci. Rep., 7:46024, 2017.
• Gao, M., Igata, H., Takeuchi, A., Sato, K., Ikegaya, Y. Machine learning-based prediction of adverse drug effects: an example of seizure-inducing compounds. J. Pharmacol. Sci., 133:70-78, 2017.
• 鹿野悠、佐々木拓哉、池谷裕二、海馬神経細胞の時間表象、Brain and Nerve、69: 1233-1239, 2017.
• 笠原 由佳、池谷 裕二、小山 隆太、マウス熱性けいれんモデルの作製、日本薬理学雑誌、150: 240-245, 2017.
• 八幡洋輔、佐々木拓哉、動物の個性を考慮した行動解析、日本薬理学雑誌、150: 116, 2017.
• 佐々木拓哉、海馬の場所細胞と病態研究、日本薬理学雑誌、149: 247, 2017.
• 佐々木拓哉、中枢末梢連関の理解に向けた生体電気信号の網羅的解析、日本薬理学雑誌、149: 167-172, 2017.
• 岡田桜、青木勇樹、佐々木拓哉、池谷裕二、海馬研究の最前線、Brain and Nerve、69:453-460, 2017.
• 佐村俊和、池谷裕二、佐藤能臣、海馬CA3培養スライスの自発的な神経発火を再現する神経回路の推定、生物物理、57:33-35, 2017.
• 池谷裕二、脳回路活動の構造解析、ブレインサイエンス・レビュー、43-58, 2017.

2016

• Matsumoto, N. Okamoto, K., Takagi, Y., Ikegaya, Y. 3-Hz subthreshold oscillations of CA2 neurons in vivo. Hippocampus, 26:1570-1578, 2016.
• Funayama, K., Hagura, N., Ban, H., Ikegaya, Y. Functional organization of flash-induced V1 offline reactivation. J. Neurosci., 36:11727-11738, 2016.
• Luo, C., Ikegaya, Y., Koyama, R. Microglia and neurogenesis in the epileptic dentate gyrus. Neurogenesis, 3:e1235525, 2016.
• Mikami, Y., Kanemaru, K., Okubo, Y., Nakaune, T., Suzuki, J., Shibata, K., Sugiyama, H., Koyama, R., Murayama, T., Ito, A., Yamazawa, T., Ikegaya, Y., Sakurai, T., Saito, N., Kakizawa, S., Iino, M. Nitric Oxide-induced Activation of the Type 1 Ryanodine Receptor Is Critical for Epileptic Seizure-induced Neuronal Cell Death. EBioMedicine, 11:253-261, 2016.
• Okada, S., Igata, H., Sakaguchi, T., Sasaki, T., Ikegaya, Y. A new device for the simultaneous recording of cerebral, cardiac, and muscular electrical activity in freely moving rodents. J. Pharmacol. Sci., 32:105-108, 2016.
• Kasahara, Y., Koyama, R., Ikegaya, Y. Depth and time-dependent heterogeneity of microglia in mouse hippocampal slice cultures. Neurosci. Res., 111:64-69, 2016.
• Makino, K., Funayama, K., Ikegaya, Y. Re-analysis on geometric energy. Anat. Sci. Int., 91:425-426, 2016.
• Ando, M., Koyama, R ., Ikegaya, Y. Severity of kainic acid-induced seizures is not aggravated in the maternal immune activation mouse model of gestational poly(I:C) exposure. J. Autism Epilepsy, 1:1003, 2016.
• Hirabayashi, K., Hanaoka, K., Egawa, T., Kobayashi, C., Takahashi, S., Komatsu, T., Ueno, T., Terai, T., Ikegaya, Y., Nagano, T., Urano, Y. Development of practical red fluorescent probe for cytoplasmic calcium ions with greatly improved cell-membrane permeability. Cell Calcium, 17:27, 2016.
• Luo, C. Koyama, R. Ikegaya, Y. Microglia engulf viable newborn cells in the epileptic dentate gyrus. Glia, 64:1508-1517, 2016.
• Ihara, N., Nakashima, A., Hoshina, N., Ikegaya, Y. Takeuchi, H. Differential expression of axon-sorting molecules in mouse olfactory sensory neurons. Eur. J. Neurosci., 44:1998-2003, 2016.
• Takeda, A., Nomura, H., Masamitsu, N., Matsuki, N., Ikegaya, Y., Terai, T., Ueno, T., Hanaoka, K., Nagano, T., Urano, Y., Komatsu, T. Unexpected photo-instability of 2,6-sulfonamide-substituted BODIPYs and its application to development of caged GABA. Chembiochem, 17:1233-1240, 2016.
• Nishimura, R., Abe, R., Sasaki, T., Ikegaya, Y. Homeostatic changes in neuronal network oscillations in response to continuous hypoperfusion in the mouse forebrain. Neurosci. Res., 109:28-34, 2016.
• Okada, M. Ishikawa, T. Ikegaya, Y. A computationally efficient filter for reducing shot noise in low S/N data. PLOS One, 11:e0157595, 2016.
• Oba, S., Nakae, K., Ikegaya, Y., Aki, S., Yoshimoto, J., Ishii, S. Empirical Bayesian significance measure of neuronal spike response. BMC Neurosci., 17:27, 2016.
• Ohki, M., Sugiyama, K., Kawai, F., Tanaka, H., Nihei, Y., Unzai, S., Takebe, M., Matsunaga, S., Adachie, S., Shibayama, N., Zhou, Z., Koyama, R., Ikegaya, Y., Takahashi, T., Tame, J.R.H., Iseki, M., Park, S.Y. Structural basis for photoactivation of a light-regulated adenylate cyclase from the photosynthetic cyanobacterium Oscillatoria acuminatea. Proc. Natl. Acad. Sci. U. S. A., 113:6659-6664, 2016.
• Nakayama, R., Sasaki, T., Tanaka, K. F., Ikegaya, Y. Subcellular calcium dynamics during juvenile development in mouse hippocampal astrocytes. Eur. J. Neurosci., 43:923-932, 2016.
• Igata, H., Sasaki, T., Ikegaya, Y. Early failures benefit subsequent task performance. Sci. Rep., 6:21293, 2016.
• Nakayama, D., Hashikawa-Yamasaki, Y., Ikegaya, Y., Matsuki, N., Nomura, H. Late Arc/Arg3.1 expression in the basolateral amygdala is essential for persistence of newly-acquired and reactivated contextual fear memories. Sci. Rep., 6:21007, 2016.
• Tao, K., Ichikawa, J., Matsuki, N., Ikegaya, Y., Koyama, R. Experimental febrile seizures induce age-dependent structural plasticity and improve memory in mice. Neuroscience, 318:34-44, 2016.
• Takahashi, N., Kobayashi, C., Ishikawa, T., Ikegaya, Y. Subcellular imbalances in synaptic activity. Cell Rep., 14:1348-1354, 2016.
• Sajo, M., Sugiyama, H., Yamamoto, H., Tanii, T., Matsuki , N., Ikegaya, Y., Koyama, R. Neuraminidase-dependent degradation of polysialic acid is required for the lamination of newly generated neurons. PLOS One, 11:e0146398, 2016.
• Zhou, Z., Tanaka, K. F., Matsunaga, S., Iseki, M., Watanabe, M., Matsuki , N., Ikegaya, Y., Koyama, R. Photoactivated adenylyl cyclase (PAC) reveals novel mechanisms underlying cAMP-dependent axonal morphogenesis. Sci. Rep., 5:19679, 2016.
• Makino, K., Funayama, K., Ikegaya, Y. Spatial clusters of constitutively active neurons in mouse visual cortex. Anat. Sci. Int., 91:188?195, 2016.
• Koyama, R. Dentate circuitry as a model to study epileptogenesis. Biol. Pharm. Bull. 39:891-896, 2016.
• 安藤めぐみ、池谷裕二、小山隆太、自閉スペクトラム症とてんかん、日本薬理学雑誌、148:121-122, 2016.

2015

• Szymanska, A. F., Kobayashi, C., Norimoto, H., Ishikawa, T., Ikegaya, Y., Nenadic, Z. Accurate detection of low signal-to-noise ratio neuronal calcium transient waves using a matched filter. J. Neurosci. Meth., 259:1?12, 2015.
• Hitora-Imamura, N., Miura, Y., Teshirogi, C., Ikegaya, Y., Matsuki, N., Nomura, H. Prefrontal dopamine regulates fear reinstatement through the downregulation of extinction circuits. eLife, 4:e08274, 2015.
• Nomura, H., Hara, K., Abe, R., Hitora-Imamura, N., Nakayama, R., Sasaki, T., Matsuki, N., Ikegaya, Y. Memory formation and retrieval of neuronal silencing in the auditory cortex. Proc. Natl. Acad. Sci. U. S. A., 112:9740-9744, 2015.
• Funayama, K., Minamisawa, G., Matsumoto, N., Ban, H., Chan, A. W., Matsuki, N., Murphy, T. H., Ikegaya, Y. Neocortical rebound depolarization enhances visual perception. PLOS Biol., 13:e1002231, 2015.
• Asada, A., Ujita, S., Nakayama, R., Oba, S., Ishii, S., Matsuki, N., Ikegaya, Y. Subtle modulation of ongoing calcium dynamics in astrocytic microdomains by sensory inputs. Physiol. Rep., 3:e12454, 2015.
• Hongo, Y., Ogawa, K., Takahara, Y., Takasu, K., Royer, S., Hasegawa, M., Sakaguchi, G., Ikegaya, Y. Topological organization of CA3-to-CA1 excitation. Eur. J. Neurosci., 42:2135-2143, 2015.
• Hongo, Y., Takasu, K., Ikegaya, Y., Hasegawa, M., Sakaguchi, G., Ogawa, K. Heterogeneous effects of antiepileptic drugs in an in vitro epilepsy model: a functional multineuron calcium imaging study. Eur. J. Neurosci., 42:1818-1829, 2015.
• Kitanishi, T., Ujita, S., Fallahnezhad, M., Kitanishi, N., Ikegaya, Y., Tashiro, A. Novelty-induced phase-locked firing to slow gamma oscillations in the hippocampus: requirement of synaptic plasticity. Neuron, 86:1265-1276, 2015.
• Ishikawa, T., Okamoto, K., Ikegaya, Y. Homeostatic hippocampal activity against reduced glutamatergic neurotransmission. Int. J. Pharmacol., 11:318-326, 2015.
• Shimazaki, H., Sadegh, K., Ishikawa, T., Ikegaya, Y., Toyoizum, T. Simultaneous silence organizes structured higher-order interactions in neural populations. Sci. Rep., 5:9821, 2015.
• Norimoto, H., Ikegaya, Y. Visual cortical prosthesis with a geomagnetic compass restores spatial navigation in blind rats. Curr. Biol., 21:1091?1095, 2015.
• Iwasaki, S., Sakaguchi, T., Ikegaya, Y. Brief fear preexposure facilitates subsequent fear conditioning. Neurosci. Res., 95:66?73, 2015.
• Nakayama, D., Iwata, H., Teshirogi, C., Ikegaya, Y., Matsuki, N., Nomura, H. Long-delayed expression of the immediate early gene Arc/Arg3.1 refines neuronal circuits to perpetuate fear memory. J. Neurosci., 5:819?830, 2015.
• Nakayama, D., Baraki, Z., Onoue, K., Ikegaya, Y., Matsuki, N., Nomura, H. Frontal association cortex is engaged in stimulus integration during associative learning. Curr. Bol., 25:117-123, 2015.
• Koyama, R., Ikegaya Y., Microglia in the pathogenesis of autism spectrum disorders. Neurosci. Res., 100:1-5, 2015.
• Samura, T., Ikegaya, Y., Sato, Y. D. A neural network model of reliably optimized spike transmission. Cogn. Neurodyn., 9:265-77, 2015.
• 西村侑也、杉山弘樹、池谷裕二、Q&A-神経科学の素朴な疑問、Clin. Neurosci.、 33:1434, 2015.
• 小島弘人、坂口哲也、池谷裕二、記憶の脳回路痕跡、Brain and Nerve、67:599-604, 2015.
• 高木夕貴、杉山弘樹、池谷裕二、海馬における記憶再生のメカニズム、Clin. Neurosci.、33:225-225, 2015.

2014

• Nakae, K., Ikegaya, Y., Ishikawa, T., Oba, S., Urakubo, H., Koyama, M., Ishii, S. A statistical method of identifying interactions in neuron?glia systems based on functional multicell calcium imaging. PLOS Comput. Biol., 10:e1003949, 2014.
• Abe, R., Sakaguchi, T., Kitajo, K., Ishikawa, D., Matsumoto, N., Matsuki, N., Ikegaya, Y. Sound-induced modulation of hippocampal theta oscillations. Neuroreport, 25:1368-1374, 2014.
• Okamoto, K., Ishikawa, T., Abe, R., Ishikawa, D., Kobayashi, C., Mizunuma, M., Norimoto, H., Matsuki, N., Ikegaya, Y. Ex vivo cultured neuronal networks emit in vivo-like spontaneous activity. J. Physiol. Sci., 64:421-431, 2014.
• Miyawaki, T., Norimoto, H., Ishikawa, T., Watanabe, Y., Matsuki, N., Ikegaya, Y. Dopamine receptor activation reorganizes neuronal ensembles during hippocampal sharp waves in vitro. PLOS One, 9:e104438, 2014.
• Nonaka, A., Toyoda, T., Miura, Y., Hitora-Imamura, N., Naka, M., Eguchi, M., Yamaguchi, S., Ikegaya, Y., Matsuki, N., Nomura, H. Synaptic plasticity associated with a memory engram in the basolateral amygdala. J. Neurosci., 34:9305?9309, 2014.
• Tao, K., Matsuki, N., Koyama, R., AMP-activated protein kinase mediates activity-dependent axon branching by recruiting mitochondria to axon. Dev. Neurobiol., 74:557-573, 2014.
• Abe, R., Sakaguchi, T., Matsumoto, N., Matsuki, N., Ikegaya, Y. Sound-induced hyperpolarization of hippocampal neurons. Neuroreport, 25:1013-1017, 2014.
• Onoue, K., Nakayama, D., Ikegaya, Y., Matsuki, N., Nomura, H. Fear extinction requires Arc/Arg3.1 expression in the basolateral amygdala. Mol. Brain, 7:30, 2014.
• Sasaki, T., Ishikawa, T., Abe, R., Nakayama, R., Asada, A., Matsuki, N., Ikegaya, Y. Astrocyte calcium signaling orchestrates neuronal synchronization in organotypic hippocampal slices. J. Physiol., 592:2771-2783, 2014.
• Sasaki, T., Matsuki, N., Ikegaya, Y. Interneuron firing precedes sequential activation of neuronal ensembles in hippocampal slices. Eur. J. Neurosci., 39:2027-2036, 2014.
• Ishikawa, D., Matsumoto, N., Sakaguchi, T., Matsuki, N., Ikegaya, Y. Operant conditioning of synaptic and spiking activity patterns in single hippocampal neurons. J. Neurosci., 34:5044-5053, 2014.
• Mizunuma, M., Norimoto, H., Tao, K., Egawa, T., Hanaoka, K., Sakaguchi, T., Hioki, H., Kaneko, T., Yamaguchi, S., Nagano, T., Matsuki, N., Ikegaya, Y. Unbalanced excitability underlies offline reactivation of behaviorally activated neurons. Nat. Neurosci., 17:503-505, 2014.
• Kobayashi, C., Ohkura, M., Nakai, J., Matsuki, N., Ikegaya, Y., Sasaki, T. Large-scale imaging of subcellular calcium dynamics of cortical neurons with G-CaMP6-actin. Neuroreport, 25:501-506, 2014.

Before 2013 (selected)

• Koyama, R., Tao, K., Sasaki, T., Ichikawa, J., Miyamoto, D., Muramatsu, R., Matsuki, N., Ikegaya, Y. GABAergic excitation after febrile seizures induces ectopic granule cells and adult epilepsy. Nat. Med., 18:1271-1278, 2012.
• Takahashi, N., Kitamura, K., Matsuo, N., Mayford, M., Kano, M., Matsuki, N., Ikegaya, Y. Locally synchronized synaptic inputs. Science, 335:353-356, 2012.
• Sasaki, T., Matsuki, N. Ikegaya, Y. Action-potential modulation during axonal conduction. Science, 311:599-601, 2011.